Test The Effectiveness Of Japanese Papaya Leaf Extract (Cnidoscolus aconitifolius) On Aedes aegypti Larvae Mortality


Uji Efektivitas Ekstrak Daun Pepaya Jepang (Cnidoscolus aconitifolius) Terhadap Mortalitas Larva Aedes aegypti


  • (1) * Syahrul Ardiansyah            Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo  
            Indonesia

  • (2)  Faizatun Nafsi              
            Indonesia

  • (3)  Galuh Ratmana Hanum            Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo  
            Indonesia

    (*) Corresponding Author

Abstract

Dengue hemorrhagic fever (DHF) is caused by the dengue virus which is transmitted through the bite of the Aedes aegypti mosquito. Prevention of DHF can be done by using larvicides. Synthetic chemical larvicides are considered to have side effects in long-term use and can cause environmental pollution. So we need an alternative larvicides with natural ingredients from plants, namely Japanese Papaya plants. This study aims to determine the effectiveness of Japanese Papaya (Cnidoscolus aconitifolius) leaf extract on the mortality of Aedes aegypti larvae. This type of research uses an experimental study design. This study used 6 treatments with 4 repetitions consisting of control without treatment, P1 (0.2%), P2 (0.4%), P3 (0.6%), P4 (0.8%), and P5 (1%). Observations were made for 48 hours. From the research results obtained LC50 of 1.095%. The results of statistical tests using One-Way ANOVA showed that there was a significant effect on the mortality of mosquito larvae.

 

References

Awoyinka, O. A., Balogun, I. O., & Ogunnowo, A. A. (2007). Phytochemical screening and in vitro bioactivity of Cnidoscolus aconitifolius (Euphorbiaceae). Journal of Medicinal Plants Research, 1(3), 63–65. Retrieved from http://www.academicjournals.org/JMPR

Cania, E., & Setyaningrum, E. (2013). Uji Efektivitas Larvasida Ekstrak Daun Legundi (Vitex Trifolia) Terhadap Larva Aedes aegypti. Jurnal Majority, 2(4), 52–60. Retrieved from https://juke.kedokteran.unila.ac.id/ index. php/majority/article/view/62

Harfriani, H. (2012). Efektivitas Larvasida Ekstrak Daun Sirsak dalam Membunuh Jentik Nyamuk. Jurnal Kesehatan Masyarakat, 7(2), 164–169. doi: 10.15294/kemas.v7i2.2813

Hairani, S., Soviana, S., & Supriyono. (2014). Efektivitas Ekstrak Daun Mundu (Garcinia dulcis) Sebagai Larvasida Nyamuk Culex quinquefasciatus dan Aedes aegypti. IPB University Scientific Repository. Retrieved from http://repository. ipb.ac.id/handle/123456789/72391

Hernandez, I. M. S., Alvarez, C. P. B., Gonzalez, O. R. T., dan Camberos, E. P. (2017). Nutraceutical Potential of Cnidoscolus aconitifolius. ARC Journal of Nutrition and Growth, 3(2), 27–30. Retrieved from https://www.arcjournals.org/journal-of-nutrition-and-growth/volume-3-issue-2/5 DOI: https://doi.org/10.20431/2455-2550.0302005

Harnandez, H. P. (2017). Direct Instruction in Second Language Acquisition: A Critical Review of Related Literature. Journal on English Language Teaching, 7(1), 43-56. doi: 10.26634/JELT.7.1.11406 DOI: https://doi.org/10.26634/jelt.7.1.11406

Jimenéz-Arellanes, M. A., García-Martínez, I., & Rojas-Tome, S. (2014). Potencial biológico de especies medicinales del género Cnidoscolus (Euphorbiacea). Revista Mexicana de Ciencias Farmacéuticas, 45(4), 1-6. Retrieved from https://www.redalyc.org/pdf/579/57940028003.pdf

Kementerian Kesehatan RI. (2017). Profil Kesehatan Indonesia. Jakarta: . Kementrian Republik Indonesia.

Kemenkes RI. (2020). Profil Kesehatan Indonesia Tahun 2019. In Kementrian Kesehatan Republik Indonesia. Kementrian Kesehatan Republik Indonesia. Retrieved from https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf

Kementerian Kesehatan RI. (2018). Situasi Penyakit Demam Berdarah Di Indonesia 2017. In Journal of Vector Ecology, 31(1), 71–78. Retrieved from: https://www.kemkes.go.id/download.php?file=download/pusdatin/infodatin/InfoDatin-Situasi-Demam-Berdarah-Dengue.pdf

Kemenkes. (2017). Pedoman Pencegahan Dan Pengendalian Demam Berdarah Dengue Di Indonesia. Jakarta: Kementerian Kesehatan Republik Indonesia. Retrieved from https://drive.google.com/file/d/ 1IATZEcgGX3x3BcVUcO_l8Yu9B5REKOKE/view

Lamin, S., Nofyan, E., & Putri, B. Y. (2019). Uji Aktivitas Larvasida Fraksi Aktif Daun Bakau Minyak (Rhizophora apiculata blume) Terhadap Larva Nyamuk Aedes aegypti Linn. In Prosiding Seminar Nasional Perhimpunan Entomologi Indonesia (PEI) Cabang Palembang, 1(1), 518-530. Retrieved from http://digilib.unsri.ac.id//index.php?p=show_1

Logaswamy, S., & Remia, K. (2010). Mosquito Adulticidal Properties of Delonix Elata (Family: Fabaceae) Against Dengue Vector, Aedes aegypti (Diptera: Culicidae). Journal of Coastal Life Medicine, 208–2(5), 389-393. doi: 10.12980/jclm.2.2014jclm-2014-0024 DOI: https://doi.org/10.12980/JCLM.2.2014JCLM-2014-0024

Nisa, K., Hargono, A., dan Ridha, M. R. (2012). Aedes aegypti in Sekumpul Village (Martapura-District of Banjar, South Kalimantan) is tolerant to Temephos. Jurnal Buski, 4(2), 21421. Retrieved from https://www.neliti.com/id/publications/21421/aedes-aegypti-in-sekumpul-village-martapura-district-of-banjar-south-kalimantan

Nurhaifah, D., & Sukesi, T. W. (2015). Efektivitas Air Perasan Kulit Jeruk Manis sebagai Larvasida Nyamuk Aedes aegypti. Jurnal Kesehatan Masyarakat Nasional, 9(3), 207-213. Retrieved from https:// media.neliti.com/ media/publications/39889-ID-efektivitas-air-perasan-kulit-jeruk-manis-sebagai-larvasida-nyamuk-aedes-aegypti.pdf DOI: https://doi.org/10.21109/kesmas.v9i3.566

Prakoso, G., Aulung, A., dan Citrawati, M. (2016). Uji Efektivitas Ekstrak Buah Pare (Momordica charantia) Pada Mortalitas Larva Aedes aegypti. Jurnal Profesi Medika, 46–53. doi: 10.33533/jpm.v10i1.13 DOI: https://doi.org/10.33533/jpm.v10i1.13

Pratiwi, Pandji, C., & Amin, C. (2010). Perbandingan Metode Maserasi, Remaserasi, Perkolasi dan Reperkolasi dalam Ekstraksi Senyawa Aktif Andrographolide dari Tanaman Sambiloto (Andrographis paniculata (Burm.F.) Nees). IPB University Scientific Repository. Retrieved from http://repository.ipb.ac.id/handle/123456789/62199

Rahmawati, L. (2018). Pengaruh Ekstrak Etanol Daun Kates Jepang (Cnidoscollus aconotyfolius) Terhadap Hiperkolesterolemia Pada Tikus Putih (Rattus Norvegicus) dan Pemanfaatanya. Retrieved from http:// repository. unej.ac.id/handle/ 123456789/92130

Rustam, R., dan Fitri, N. (2022). Uji Beberapa Konsentrasi Ekstrak Daun Pepaya Jepang (Cnidoscolus aconitifolius I.M. Johnst) untuk Mengendalikan Ulat Grayak Jagung (Spodoptera frugiperda J. E. Smith) di Laboratorium. Prosiding Seminar Nasional dan Pra Lokaraya Nasional, Digitalisasi Pertanian Menuu Kebangkitan Ekonomi Kreatif. Retrieved from http://repository.unwmataram.ac.id/2332/1/Buku%20Abstrak%20Semnas%20FP%20UNS%202022.pdf

Sari, S. N., Prastiwi, R., dan Hayati, H. (2022). Studi Farmakognosi, Fitokimia Dan Aktivitas Farmakologi Tanaman Pepaya Jepang (Cnidoscolus aconitifolius (Mill.) I.M. Johnston). Jurnal Ilmiah Ilmu Kefarmasian, 9(1), 1-15. doi: 10.22236/ farmasains.v9i1.5403 DOI: https://doi.org/10.22236/farmasains.v9i1.5403

Sutanto, I., Ismid, I. S., Sjarifuddin, P. K., & FKUI, D. P. (2017). Buku ajar

Parasitologi Kedokteran (S. S. Inge Sutanto, Is Suhariah Ismid, Pudji K. Sjarifuddin (ed.); Keempat). Badan Penerbit Fakultas Kedokteran Universitas Indonesia. Retrieved from https://opac.perpusnas.go.id/ DetailOpac. aspx?id= 1145496

Suardi. (2019). Pengaruh Kepuasan Kerja terhadap Kinerja Pegawai Pada PT Bank Mandiri, Tbk Kantor Cabang Pontianak. Business, Economics and Entrepreneurship, 1(2), 9-19. doi: 10.16021/b.e.e..v1i2.124 DOI: https://doi.org/10.46229/b.e.e..v1i2.124

Utomo, M., Wardani, R. S., & Amri, S. (2020). Pengeruh Jumlah Air yang di Tambahkan Pada Kemasan Serbuk Bunga Sukun (Artocarpus communis) Sebagai Pengganti Isi Ulang Obat Nyamuk Elektrik Terhadap Lama Waktu Efektif Daya Bunuh Nyamuk Anopheles aconitus Lapangan. Jurnal Kesehatan Masyarakat Indonesia, 6(1), 15–23. doi: 10.26714/jkmi.6.1.2010.%25p

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Published
2023-07-31
 
How to Cite
Ardiansyah, S., Nafsi, F., & Hanum, G. R. (2023). Test The Effectiveness Of Japanese Papaya Leaf Extract (Cnidoscolus aconitifolius) On Aedes aegypti Larvae Mortality . Medicra (Journal of Medical Laboratory Science/Technology), 6(1), 25-31. https://doi.org/10.21070/medicra.v6i1.1671
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Articles

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