Relationship of Candida albicans Urinary Colony Count and Glucosuria in Elderly Diabetics

Hubungan Jumlah Koloni Candida albicans Urin dan Glukosuria pada Lansia Penderita Diabetes

Authors

  • Nadyah Saffana Fadhilla Program Studi Sarjana Terapan Teknologi Laboratorium Medis, Sekolah Tinggi Ilmu Kesehatan Nasional, Surakarta, Jawa Tengah, Indonesia
  • Muhammad Taufiq Qurrohman Program Studi Sarjana Terapan Teknologi Laboratorium Medis, Sekolah Tinggi Ilmu Kesehatan Nasional, Surakarta, Jawa Tengah, Indonesia

DOI:

https://doi.org/10.21070/medicra.v8i2.1800

Keywords:

Diabetes Mellitus, Candida albicans, Elderly, Glucosuria, Urine Culture

Abstract

Diabetes mellitus is a global health problem with a high prevalence in the elderly and is associated with an increased risk of opportunistic infections. One of the common accompanying conditions is glucosuria, caused by elevated urinary glucose excretion, which may promote the growth of Candida albicans. This study aimed to examine the relationship between urinary glucosuria and the number of Candida albicans colonies in elderly patients with diabetes mellitus at Griya Sehat Colomadu Clinic. Urine samples were tested for glucosuria using the dipstick method, while urine cultures were performed on CHROMagar Candida medium to identify and quantify Candida albicans colonies. Data were analyzed using the Spearman correlation test. Most respondents were negative for glucosuria (57,14%), while the remainder were positive with varying degrees. The colony counts of Candida albicansranged from 0 to 319.000 CFU/mL, with median counts increasing alongside the degree of glucosuria. Statistical analysis revealed a strong and significant positive correlation between glucosuria and Candida albicans colony counts (r = 0,700; p < 0.01). Higher levels of glucosuria are associated with increased Candida albicans colony counts in the urine of elderly patients with diabetes mellitus. These findings highlight the importance of controlling blood glucose levels and routinely monitoring urine cultures to prevent opportunistic fungal infections in elderly diabetic patients. 

References

Az-zahro, F., Kristinawati, E., & Fikri, Z. (2021). Hubungan Antara Kandidiasis Pada urine Wanita Penderita Diabetes Mellitus Dengan Nilai Positivitas Glukosuria Di Wilayah Kerja Puskesmas Narmada. Jurnal Analis Medika Biosains (JAMBS), 8(2), 92-98. Doi: 10.32807/jambs.v8i2.239

Deng, R., Meng, X., Li, R., Wang, A., & Song, Y. (2023). Asymptomatic Candida glabrata urinary tract infection in an immunocompetent young female A case report. Medicine (United States), 102(20), E33798. Doi: 10.1097/MD.0000000000033798

Dinkes Jateng (2023). Buku Profil Kesehatan. https://dinkes.jatengprov.go.id/buku-profil-kesehatan-v2

Ekawati, I. A. P., Ni, W. D. B., Sri, I., & Ida, A. M. D. (2023). Gambaran Jamur Candida albicans Pada Urin Pra-Menstruasi Mahasiswi Stikes Wira Medika Bali. Jurnal Riset Kesehatan Nasional, 7(2), 84–90. Retrieved from https://ejournal.itekes-bali.ac.id/jrkn

Hiyama, Y., Sato, T., Takahashi, S., Yamamoto, S., Ogasawara, N., Masumori, N., & Yokota, S. ichi. (2022). Reduction of susceptibility to azoles and 5-fluorocytosine and growth acceleration in Candida albicans in glucosuria. Diagnostic Microbiology and Infectious Disease, 102(1), 115556. Doi: 10.1016/j.diagmicrobio.2021.115556

Karwiti, W., Asrori, A., Garini, A., & Akbar, B. M. (2022). Keberadaan Candida albicans Pada Urine Penderita Diabetes Mellitus Di Rumah Sakit. Jambura, 4(0), 99-105. Doi: 10.35971/jjhsr.v4i0.13070

Kim, S. J., Ryu, J. H., Kim, Y. B., & Yang, S. O. (2019). Management of Candida Urinary Tract Infection in the Elderly. Urogenital Tract Infection, 14(2), 33. https://doi.org/10.14777/uti.2019.14.2.33

Liang, B., Tang, W. W., Zhang, W. Q., Huang, C., Liu, Y., Xu, F., Liu, X., Yuan, N., Liu, J. X., Yi, Y. J., Xu, R. H., Hu, D., Huang, X. B., & Cao, X. (2020). Prevalence and Associated Factors of Diabetes Mellitus in a Very Elderly Chinese Population: A Cross-sectional Study. Biomedical and Environmental Sciences, 33(5), 315–322. https://doi.org/10.3967/bes2020.043

Muhajir, N. F., Nadifah, F., Arisandi, D., & Susliyanti, M. (2020). Identifikasi Candida Sp Dalam Urine Penderita Diabetes Mellitus Tipe 2 Di Puskesmas Ngemplak 2 Kabupaten Sleman Yogyakarta. Jurnal Mitra Kesehatan, 3(1), 41–46. https://doi.org/10.47522/jmk.v3i1.50

Napitupulu, L. (2021). Gambaran hasil pemeriksaan glukosa urin menggunakan metode benedict dan carik celup pada penderita diabetes melitus. The Indonesian Journal of Medical Laboratory, 2(1), 12–17.retrieved from https://ijml.jurnalsenior.com/index.php/ijml/article/view/14/13

Ngazizah, F. N., & Sobirin, M. (2023). Identifikasi Spesies Candida Sp. Pada Urine Penderita Diabetes Mellitus. Journal of Biotropical Research and Nature Technology, 1(2), 90–95. Doi: 10.52850/borneo

Ningrum, A. P., & Qurrohman, M. T. (2024). Gambaran Jumlah Koloni Candida albicans Terhadap Kadar Gula Darah Sewaktu Pada Wanita Penderita Diabetes Mellitus. Klinikal Sains : Jurnal Analis Kesehatan, 12(1), 81–90. https://doi.org/10.36341/klinikal_sains.v12i1.4632

Nurfajrina, F. R., Nur, N., Herawati, E., Malinda, Y., Mahasiswa, S., & Padjadjaran, U. (2020). Jumlah Koloni Candida Albicans Pada Penderita Hipertensi. B-Dent: Jurnal Kedokteran Gigi Universitas Baitturahmah, 7(1), 48–57. Doi: 10.33854/jbd.vlil.471

Patricia,A., Yani, A., Hanifa, N, P. (2022). Gambaran Candida albicans Pada Urin Penderita Diabetes Mellitus Di Puskesmas Neglasari. Journal of Medical Laboratory and Science, 2(6), 16–22. Doi: 10.36086/medlabscience.v2i1

Purwitaningsih, A., & Setya, A. K. (2023). Pemeriksaan Jamur Candida albicans pada Urine Penderita Diabetes Melitus di Rumah Sakit Umum Islam Klaten. Anakes : Jurnal Ilmiah Analis Kesehatan, 9(1), 33–41. Doi: 10.37012/anakes.v9i1.898

Saeedi, P., Petersohn, I., Salpea, P., Malanda, B., Karuranga, S., Unwin, N., Colagiuri, S., Guariguata, L., Motala, A. A., Ogurtsova, K., Shaw, J. E., Bright, D., & Williams, R. (2019). Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Research and Clinical Practice, 157, 107843. Doi: 10.1016/j.diabres.2019.107843

Sari, N, A., Soviana, E., Rusjianto. (2022). Kepatuhan Diet Dengan Kadar Glukosa Darah Pada Lansia Diabetes Mellitus Di Puskesmas Sangkrah Kota Surakarta. Indonesian Journal of Nutrition Science and Food, 1(1), 9–16. Retrieved from https://share.google/IUISvk5VYmoWwNJw7

Sihotang, S, F., Harahap, F, S, W., & Mazaly, M, R. (2024). Pendekatan Korelasi Pearson Dan Spearman Dalam Menganalisis Hubungan Penggunaan Bahan Ajar Berbasis Daring Dan Prestasi Akademik Mahasiswa. MES : Journal of Mathematics Education and Science. Vol 10,(1). Retrieved from https://jurnal.uisu.ac.id/index.php/mesuisu.

Sintia, I., Pasarella, M. D., & Nohe, D. A. (2022). Perbandingan Tingkat Konsistensi Uji Distribusi Normalitas Pada Kasus Tingkat Pengangguran di Jawa. Prosiding Seminar Nasional Matematika, Statistika, Dan Aplikasinya, 2(2), 322–333. Retrieved from https://share.google/9WI6i2M3LeGP5Fkva

Virginia, Z., Iskandar, E. K., Tasya, A., & Agus, A. W. (2025). Meta-Analisis: Jamur Candida dari Penyebab, Gejala, dan Efektivitas Pengobatan Berdasarkan Studi Terbaru. Jurnal Sintesis, 6(1), 8–13. Retrieved from https://share.google/Dr3ZeUZOV5vU7rTI2

Downloads

Additional Files

Published

2025-12-31

How to Cite

Fadhilla, N. S., & Qurrohman, M. T. (2025). Relationship of Candida albicans Urinary Colony Count and Glucosuria in Elderly Diabetics: Hubungan Jumlah Koloni Candida albicans Urin dan Glukosuria pada Lansia Penderita Diabetes . Medicra (Journal of Medical Laboratory Science Technology), 8(2), 82–87. https://doi.org/10.21070/medicra.v8i2.1800

Issue

Section

Articles