Correlation Between Serology Test Result of Leptospira sp. With The Representation of Histopathological Lesions on The Cattle Kidneys Hubungan Hasil Uji Serologis Leptospira sp. dengan Representasi Lesi Histopatologis pada Ginjal Sapi
Article Sidebar
Main Article Content
Abstract
Leptospirosis is an eminent diseases among human and animal health. As a zoonosis disease, the occurrence of leptospirosis is not clearly understood in animal. Furthermore, the lesion caused by Leptospira sp. is not well demonstrated. This study aimed to analyze the correlation between the result of serological test using microscopic agglutination test (MAT) and the representation of histopathological lesion in kidney from the cattle. This study used 28 samples consist of cattle serum and kidney organs. The serum was tested using MAT and kidney was tested using histopathology. The data was reported semi quantitatively and tested using Spearman test. The result showed that there is no correlation between the result of serological test to the representation of histopathological lesion from the kidney of cattle. It is supported by the coefficient correlation (0,05) and probability value p=0,78 (p≥0,05). In conclusion, the result of Leptospira sp. serological test either seropositive or seronegative uncorrelated to the representation of histopathological lesion from the cattle kidney.
Article Details
References
Chirathaworn, C., Inwattana, R., Poovorawan, Y., & Suwancharoen, D. (2014). Interpretation of microscopic agglutination test for leptospirosis diagnosis and seroprevalence. Asian Pacific journal of tropical biomedicine, 4(Suppl 1), S162–S164.
De Brito, T., Silva, A., & Abreu, P. (2018). Pathology and pathogenesis of human leptospirosis: a commented review. Revista do Instituto de Medicina Tropical de Sao Paulo, 60, e23.
Eric Klaasen, H. L., & Adler, B. (2015). Recent advances in canine leptospirosis: focus on vaccine development. Veterinary medicine (Auckland, N.Z.), 6, 245–260.
Fávero, J. F., de Araújo, H. L., Lilenbaum, W., Machado, G., Tonin, A. A., Baldissera, M. D., Stefani, L. M., & Da Silva, A. S. (2017). Bovine leptospirosis: Prevalence, associated risk factors for infection and their cause-effect relation. Microbial pathogenesis, 107, 149–154.
Feldman, A. T., & Wolfe, D. (2014). Tissue processing and hematoxylin and eosin staining. Methods in molecular biology (Clifton, N.J.), 1180, 31–43.
Galan, D. I., Roess, A. A., Pereira, S., & Schneider, M. C. (2021). Epidemiology of human leptospirosis in urban and rural areas of Brazil, 2000-2015. PloS one, 16(3), e0247763.
Goris, M. G., Kikken, V., Straetemans, M., Alba, S., Goeijenbier, M., van Gorp, E. C., Boer, K. R., Wagenaar, J. F., & Hartskeerl, R. A. (2013). Towards the burden of human leptospirosis: duration of acute illness and occurrence of post-leptospirosis symptoms of patients in the Netherlands. PloS one, 8(10), e76549.
Haake, D. A., & Levett, P. N. (2015). Leptospirosis in humans. Current topics in microbiology and immunology, 387, 65–97.
Li, Y., Li, N., Yu, X., Huang, K., Zheng, T., Cheng, X., Zeng, S., & Liu, X. (2018). Hematoxylin and eosin staining of intact tissues via delipidation and ultrasound. Scientific reports, 8(1), 12259.
Schafbauer, T., Dreyfus, A., Hogan, B., Rakotozandrindrainy, R., Poppert, S., & Straubinger, R. K. (2019). Seroprevalence of Leptospira spp. Infection in Cattle from Central and Northern Madagascar. International journal of environmental research and public health, 16(11), 2014.
Vincent J. L. (2016). The Clinical Challenge of Sepsis Identification and Monitoring. PLoS medicine, 13(5), e1002022.