Medicra (Journal of Medical Laboratory Science/Technology) https://medicra.umsida.ac.id/index.php/medicra <p>This journal published by Medical Laboratory Technology Department, Health Science Faculty of Universitas Muhammadiyah Sidoarjo. Medicra journal published two times a year in July and December. The aim of this journal is to facilitate lecturers, researchers, and scholars for publishing the original research articles or review articles. Articles to be published on Medicra&nbsp;should follow the&nbsp;focus and scope of this journal. &nbsp;The article must have been edited according to the journal author guidelines before submitting. The scope of this journal are: Clinic Chemical,&nbsp;Hematology, Microbiology, Parasitology, Immunology, Food and beverage analysis Chemical, Molecular Diagnostics, Toxicology, Cytology, Histology, Epidemiology, Laboratory Management, and Laboratory Quality Control.</p> en-US medicra@umsida.ac.id (Andika Aliviameita, S.ST., M.Si.) editor@umsida.ac.id (Pusat Pengembangan Publikasi Ilmiah (P3I) UMSIDA) Thu, 31 Jul 2025 00:00:00 +0000 OJS 3.1.2.0 http://blogs.law.harvard.edu/tech/rss 60 Factors Contributing to the Failure of In Vitro Fertilization (IVF): A Review of Male, Female, and Laboratory-Related Causes https://medicra.umsida.ac.id/index.php/medicra/article/view/1771 <p>Infertility is big problem with some couples, infertility is an inability to get pregnancy and live birth after one year of marriage. There are many causes for this problem. In vitro fertilization (IVF) is one of the process to treat infertility. &nbsp;In vitro fertilization is includes induction of the ovaries to produce numerous oocytes, than fertilize the oocytes and development of the embryo, finally transfer the embryo. The most important reasons for repeated failure in vitro fertilization (IVF) cycle are related to the male characteristics, such as low semen concentration low sperm motility and morphology of sperm, there is a relationship between sperm quality and IVF outcome. Most of the maternal factors that contribution in decrease implantation and IVF cycle are uterine anomalies, adhesions, septa, and many more. Other factors such as body mass index (BMI), and smoking status for failure IVF. In this study review some of the causes of failure In vitro fertilization.</p> Mudhafar Abdolhussein M Copyright (c) 2025 Mudhafar Abdolhussein M http://creativecommons.org/licenses/bv/4.0/ https://medicra.umsida.ac.id/index.php/medicra/article/view/1771 Thu, 06 Mar 2025 00:00:00 +0000 Influence of Hydrocortisone on Blood Profile, Total Protein, And Glucose in Female Rabbits https://medicra.umsida.ac.id/index.php/medicra/article/view/1783 <p><span lang="EN-US">The purpose of this study is to examine how hydrocortisone affects a few blood parameters in female rabbits.&nbsp; Ten local rabbits were split into two equal and random groups.&nbsp; As a control, the first group was employed. The second group received daily intramuscular injections of hydrocortisone at a dose of 0.1 mg/kg B.W.&nbsp; Blood serum was collected every day from the first day and evaluated for total cholesterol, HDL (high-density lipoprotein), LDL (low-density lipoprotein), TG (triglycerides), and total protein after five weeks. The findings demonstrated that hydrocortisone reduced total protein and cholesterol.</span></p> Wasfi Dhahir Abid Ali Copyright (c) 2025 Wasfi Dhahir Abid Ali http://creativecommons.org/licenses/bv/4.0/ https://medicra.umsida.ac.id/index.php/medicra/article/view/1783 Fri, 30 May 2025 00:00:00 +0000 Effectiveness of Mangrove Kateng Leaf Extract (Avicennia lanata Ridl.) as a Natural Preservative for Fresh Vannamei Shrimp Meat (Litopenaeus vannamei) https://medicra.umsida.ac.id/index.php/medicra/article/view/1781 <p style="font-weight: 400;">Vannamei shrimp (<em>Litopenaeus vannamei</em>) is a mainstay export fishery product. Its meat is rich in protein and fat, but the quality is easy to reduce due to decay over storage time. Decay occurs due to bacterial activity and oxidation. The freezing preservation method requires relatively expensive costs, so it often uses hazardous materials for substitution, such as formalin as a preservative. Therefore, it is necessary to research the effectiveness of natural materials sourced from plant organs as relatively safe preservatives. One of the plants is Kateng (<em>Avicennia lanata</em>), whose leaves are rich in secondary metabolite compounds that inhibit growth and kill bacteria. This study aims to determine the effectiveness of A. lanata water extract as a natural preservative for fresh Vannamei shrimp meat. The research was an experimental laboratory study using a completely randomized design with three repetitions. The concentrations of the A. lanata water extract solution tested were 0, 25, 50, 75, and 100% (w/v). Variations in the storing time of shrimp meat after being soaked in the test extract solution were 2 and 4 hours. The storage was at room temperature. The parameters of shrimp meat quality observed at the end of the storage period included total bacterial population, hydrogen sulfide gas (H<sub>2</sub>S) production, acidity level (pH), and trimethylamine (TMA) content. The results showed that the quality of fresh Vannamei shrimp meat depends on various concentrations of A. lanata water extract solution (0-100% w/v) and storage periods (2 and 4 hours).&nbsp; Water extract of A. lanata leaves at a concentration of 75% (w/v) with 2 hours of storage is the optimal concentration and storage time to preserve fresh <em>L. vannamei</em> shrimp meat naturally.&nbsp;</p> Arkan Setia Pramudya, Arif Yachya, Suparman Suparman Copyright (c) 2025 Arkan Setia Pramudya http://creativecommons.org/licenses/bv/4.0/ https://medicra.umsida.ac.id/index.php/medicra/article/view/1781 Thu, 17 Jul 2025 23:30:17 +0000