https://medicra.umsida.ac.id/index.php/medicra <p>This journal published by Medical Laboratory Technology Department, Health Science Faculty of Universitas Muhammadiyah Sidoarjo. Medicra journal published two times a year in July and December. The aim of this journal is to facilitate lecturers, researchers, and scholars for publishing the original research articles or review articles. Articles to be published on Medicra&nbsp;should follow the&nbsp;focus and scope of this journal. &nbsp;The article must have been edited according to the journal author guidelines before submitting. The scope of this journal are: Clinic Chemical,&nbsp;Hematology, Microbiology, Parasitology, Immunology, Food and beverage analysis Chemical, Molecular Diagnostics, Toxicology, Cytology, Histology, Epidemiology, Laboratory Management, and Laboratory Quality Control.</p> Universitas Muhammadiyah Sidoarjo en-US Medicra (Journal of Medical Laboratory Science/Technology) 2580-7730 https://medicra.umsida.ac.id/index.php/medicra/article/view/1751 <p>The research included a total of 70 samples, including 40 samples from patients diagnosed with type 2 diabetes and 30 samples from the control group. The participants' age ranged from 40 to 60 years. The samples were gathered during a one-year duration from the Chronic Diseases Unit / Diabetes Department in the city of Erbil.&nbsp;&nbsp; Later, blood samples were collected from both ill and healthy individuals, and then separated via the process of centrifugation.&nbsp;&nbsp; The variables that were evaluated include glucose, ferritin, Tumor necrosis factor-alpha (TNFα), CRP, urea, creatinine, and uric acid. &nbsp;&nbsp;&nbsp;The results of this research showed a significant rise in the concentrations of glucose, ferritin, TNF-alpha, CRP, urea, creatinine, and uric acid in persons with type II diabetes as compared to the control group.</p> Zina Abdulmunem Abdulrazaaq Copyright (c) 2024 Zina Abdulmunem Abdulrazaaq http://creativecommons.org/licenses/bv/4.0/ 2024-12-31 2024-12-31 7 2 49 54 10.21070/medicra.v7i2.1751 https://medicra.umsida.ac.id/index.php/medicra/article/view/1750 <p>Smoking is a widespread public health challenge globally, impacting societal health and economy while elevating the risk of cardiovascular and peripheral vascular diseases. This study aims to examine hematological parameters (HB, PCV%, WBC, RBC, PLT, ESR), liver and kidney function, lipid profile, and electrolytes (K+, Na+, Ca++) in male smokers aged 20-55 from Baghdad City, subdivided by smoking duration (≥5 years and &lt;5 years), compared to non-smoking controls. A total of sixty participants were recruited across three areas (Diyala Bridge, Mada'in, Talbieh), with each group comprising thirty individuals. Venipuncture was performed for blood sample collection. Results revealed statistically significant elevations in total WBC and RBC counts, hematocrit, hemoglobin, total cholesterol, and liver enzymes (GOT, GPT, ALP) among smokers compared to non-smokers (p&lt;0.05 or p&lt;0.001). Serum uric acid, urea, and creatinine levels were significantly higher in smokers (p&lt;0.001), while triglyceride levels showed no significant difference (p&gt;0.05) between groups. Smokers with longer duration (&gt;5 years) exhibited higher HB, triglyceride, and Na+ levels compared to shorter-term smokers. Sensitivity analysis indicated Na+ as a potentially effective biomarker for smoking-related health impacts, complementing PCV% and urea sensitivity. The study underscores the association between smoking and oxidative stress, notably reflected in elevated GOT and GPT levels, suggesting implications for antioxidant therapies in managing smoking-induced oxidative damage. These findings contribute novel insights into biomarker responses influenced by smoking duration and advocate for targeted public health strategies and further research into antioxidant interventions to mitigate smoking-associated health risks effectively.</p> Shaymaa Saadi Abbood Aseel Khalil Ibraheem Heyam A Hashim Muntadher Hussein Challoob Copyright (c) 2024 Shaymaa Saadi Abbood http://creativecommons.org/licenses/bv/4.0/ 2024-07-25 2024-07-25 7 2 55 62 10.21070/medicra.v7i2.1750